At Medical Fakeeh, the Department of Medicine stands out as the most extensive clinical unit, boasting a team of over 45 expert physicians spread across seven specialized sections. This department is dedicated to providing sophisticated care to adult patients in various medical disciplines. The internal medicine specialists, renowned for their exceptional training and expertise, offer comprehensive outpatient services and are adept in conducting specialized procedures. The department encompasses various fields including General Internal Medicine, Gastroenterology, Infectious Diseases, Pulmonary Diseases, Rheumatology, Nephrology, and Endocrinology.

A key focus of the Department is the cultivation of an esteemed residency program at Medical Fakeeh, which equips medical students with in-depth training in various internal medicine fields, preparing them to excel as internists. The department is also notable for its significant contributions to medical research, with numerous publications in the discipline.